Research

Since nicotinamide adenine dinucleotide (NAD⁺) is a central molecule of human energy metabolism, both ageing and various diseases are often characterized by reduced NAD⁺ concentrations. To counteract this, exercise has emerged as a promising strategy to increase NAD⁺ levels (so-called NAD⁺-boosting strategy). With our project, we aim to further investigate the intensity-dependent regulation of NAD⁺ metabolism at both systemic and cellular levels. In the long term, we aim to strengthen the potential of exercise as a NAD⁺-boosting strategy, especially for the treatment of age- and disease-related changes.

Funded by: Own funds

Cooperation partners: Prof. Dr. Carsten Watzl, Leibniz Research Center for Working Environment and Human Factors; Dr. Anna Worthmann, University Medical Center Hamburg (UKE)

Project coordination: David Walzik

If you are interested in our offer or would like to receive further information, please contact us:

Participate as a test person: david.walziktu-dortmundde

Participate as a student or intern: david.walziktu-dortmundde

Spiroergometry is a standard sports medicine procedure for assessing endurance performance. It involves measuring an individual's maximal oxygen uptake (V̇O2max) and peak power output (PPO) during continuous load increase until complete exhaustion. Despite multiple fields of application, objective guidelines for the individual design of the workload are missing so far. With our project, we want to develop a mathematical model that allows a prediction of the individual PPO by recording personal data (e.g. body composition, weight, gender). Thus, by collecting simple parameters personalized exercise protocols can be designed. Besides multiple linear regressions, we also use machine learning techniques for this prediction. In the long term, we want to provide objective guidelines for the choice of exercise protocols when performing spiroergometry.

Funded by: Own funds

Cooperation partners: Juniorprof. Dr. Thomas Liebig, TU Dortmund University

Project coordination: Charlotte Wenzel

If you are interested in our offer or would like to receive further information, please contact us:

Participate as a test person: ppo.sport.fk16tu-dortmundde

Participate as a student or intern: charlotte.wenzeltu-dortmundde

The overall aim of the research project is to investigate the influence of preoperative strength and endurance training of 3-5 weeks on the subsequent recovery process in patients with diverticulitis-disease. We are interested in the effects of the training on physical performance after surgery and on systemic and tissue-specific inflammatory processes. According to a translational research approach, we also investigate aspects of social participation (quality of life, sleep quality, exercise behaviour) as well as clinically relevant parameters (complications during and after surgery, length of hospital stay).

Funded by: EDEN-Stiftung

Cooperation partners: Dr. André Schilling, Knappschaftskrankenhaus Dortmund

Project coordination: Marit Lea Schlagheck

If you are interested in our offer or would like to receive further information, please contact us:

E-mail: prehab.sport.fk16tu-dortmundde

Due to deficient services, evidence-based exercise recommendations reach people with MS with great latency and rarely take individual conditions into account. People with MS tend to reduce their physical activity after diagnosis. To counteract this, we offer interested people online free, personalised and evidence-based exercise and sports counselling and accompany them over 12 months with a total of three individual zoom meetings. In addition, this non-commercial project is scientifically accompanied and evaluated with regard to sustainability.

Funded by: German Multiple Sclerosis Society - Landesverband NRW e.V.

Project coordination: Marit Lea Schlagheck

If you are interested in our offer or would like to receive further information, please contact us:

E-mail: ms-sprechstunde.sport.fk16tu-dortmundde

With 280,000 people affected, multiple sclerosis (MS) is one of the most common autoimmune diseases in Germany. In addition to drug therapies, which are often accompanied by severe side effects, studies have shown that targeted exercise interventions alleviate symptoms of MS and improve the participant´s quality of life as well. The anti-inflammatory effect of regular exercise is proposed as a central underlying mechanism,  which has clearly been demonstrated in MS animal models. Intriguingly, data from own studies suggest that high-intensity interval training (HIIT) is superior compared to moderate endurance training in terms of beneficially affecting MS-associated biomarkers. However, it is still unclear how molecular and cellular aspects of the immune system of patients with MS are affected by a HIIT intervention lasting for several weeks. Therefore, our project aims at adding evidence to this knowledge gap which should substantiate the beneficial effects of regular intense exercise on the symptomatology and immunobiology in MS.
Funded by: Hans Böckler Foundation, German Academic Exchange Service
Cooperation partners: Prof. Dr. Carsten Watzl (Leibniz Research Center for Working Environment and Human Factors at the TU Dortmund), PD Dr. Gisa Ellrichmann (Clinical center Dortmund), Prof. Dr. Michael Linnebank (St. Barbara Hospital, Gladbeck), German Multiple Sclerosis Society North Rhine-Westphalia

Project leadership: Prof. Dr. Dr. Philipp Zimmer

Project coordination and execution: Tiffany Wences, Sebastian Proschinger

If you are interested in participating in this study or if would like to receive further information, please contact us:

Participate as a test person: MS-Sport-Studie.fk16tu-dortmundde

Participate as a student or trainee: MS-Sport-Studie.fk16tu-dortmundde

2023

• Rosenkranz S C, Ploughman M, Hvid L, Zimmer P, Erickson K, Stellmann J P, Centonze D, Friese M. The MoxFo initiative – mechanisms of action: Biomarkers in multiple sclerosis exercise studies. Mutiple Sclerosis Journal 2023. Accepted

2022

• Joisten N, Wences Chirino TY, Boßlau TK, Wasserfurth P, Hahn A, Krüger K, Zimmer P. Older adults with Cytomegalovirus (CMV) reveal increased CD8+/CD4+ EMRA cells and elevated systemic levels of kynurenic acid. Immunology 2022. DOI: 10.1111/imm.1360
• Walzik D, Jonas W, Joisten N, Belen S, Wüst R CI, Guillemin G, Zimmer P. Tissue-specific effects of exercise as NAD⁺-boosting strategy: current knowledge and future perspectives. Acta Physiologica 2022. Accepted. DOI: 10.1111/apha.13921
• Sleurs C, Amidi A, Wu LM, Kiesl D, Zimmer P, Lange M, Rogiers A, Giffard B, Binarelli G, Borghgraef C, Deprez S, Duivon M, De Ruiter M, Schagen S, Ahmed-Lecheheb D, Castel H, Buskbjerg CR, Dos Santos M, Joly F, Perrier J. Cancer-related cognitive impairment in non-CNS cancer patients: Targeted review and future action plans in Europe. Critical Reviews in Oncology/Hematology 2022. DOI: 10.1016/j.critrevonc.2022.103859
• Esser T, Zimmer P, Schier R. Preoperative exercise and prehabilitation. Current Opinion in Anesthesiology 2022. DOI: 10.1016/j.critrevonc.2022.103859
• Wolf F, Zimmer P. Multimodal agility-based exercise training for persons with Multiple Sclerosis: a new framework. Neurorehabilitation and Neural Repair 2022. DOI: 10.1177/15459683221131789
• Bauer CJ, Findlay M, Koliamitra C, Zimmer P, Schick V, Ludwig S, Gurtner GC, Riedel B, Schier R. Preoperative exercise induces endothelial progenitor cell mobilisation in patients undergoing major surgery – A prospective randomised controlled clinical proof-of-concept trial. Heliyon 2022. DOI: 10.1016/j.heliyon.2022.e10705
• Castelli L, Walzik D, Joisten N, Watson M, Montaruli A, Oberste M, Roveda E, Zimmer P. Effect of sleep and fatigue on cardiovascular performance in young healthy subjects. Physiology & Behavior 2022. DOI: https://doi.org/10.1016/j.physbeh.2022.113963
• Wolf F, Nielsen J, Saliger J, Hennecken E, Eschweiler M, Folkerts AK, Karbe H, Zimmer P. Randomised controlled pilot and feasibility study of multimodal agility-based exercise training (MAT) versus strength and endurance training (SET) to improve multiple sclerosis-related fatigue and fatigability during inpatient rehabilitation (ReFEx): study protocol. BMJ Open 2022. 12(9):e062160. DOI: 10.1136/bmjopen-2022-062160

• Hiensch A, Monninkhof E, Schmidt ME, Zopf EM, Bolam KA, Aaronson NK, Belloso J, Bloch W, Clauss D, Deppenbusch J, Lachowicz M, Pelaez M, Rundqvist H, Senkus E, Stuiver MM, Trevaskis M, Urruticoechea A, Rosenberger F, Van der Wall E, de Wit GA, Zimmer P, Wengström Y, Steindorf K, May AM. Design of a multinational randomized controlled trial to assess the effects of structured and individualized exercise in patients with metastatic breast cancer on fatigue and quality of life: the EFFECT study. Trials 2022. 23 (1). DOI:10.1186/s13063-022-06556-7
• Schenk A, Esser T, Belen S, Gunasekara N, Joisten N, Winker MT, Weike L, Heidenreich A, Herden J, Löser H, Oganesian S, Theurich S, Watzl C, Zimmer P. Distinct distribution patterns of exercise-induced natural killer cell mobilisation into the circulation and tumor tissue of patients with prostate cancer. American Journal of Physiology – Cell Physiology 2022. Accepted. DOI: 10.1152/ajpcell.00243.2022
• Javelle F, Löw A, Bloch W, Hosang T, Jacobsen T, Johnson SL, Schenk A, Zimmer P. Unraveling the Contribution of Serotonergic Polymorphisms, Prefrontal Alpha Asymmetry, and Individual Alpha Peak Frequency to the Emotion-Related Impulsivity Endophenotype. Molecular Neurobiology 2022. Accepted. DOI: 10.1007/s12035-022-02957-6
• Javelle F, Vogel A, Laborde S, Oberste M, Watson M, Zimmer P. Physical exercise is tied to emotion-related impulsivity: insights from correlational analyses in healthy humans. European Journal of Sport Science 2022. Ahead of print. DOI: 10.1080/17461391.2022.2065927
• Kiesl D, Kuzdas-Sallaberger M, Fuchs D, Brunner S, Kommenda R, Tischler C, Hornich H, Akbari K, Kellermaier J, Blessberger H, Ocenasek H, Hofmann P, Zimmer P, Vosko MR. Protocol for the Exercise, Cancer and Cognition – The ECCO-Study: A RCT of Simultaneous Exercise During Neo-/Adjuvant Chemotherapy in Breast Cancer Patients and its Effects on Neurocognition. Frontiers in Neurology 2022. 13: 777808 DOI: 10.3389/fneur.2022.777808
• Kierdorf F, Zimmer P, Joisten N, Kiesl D, Winker M, Rigoux L, Elter T.  L-kynurenine as a prognostic marker for early mortality in patients with acute myeloid leukemia. Leukemia & Lymphoma 2022 [accepted]. DOI: 10.1080/10428194.2022.2053534
• Castelli L, Elter T, Wolf F, Watson M, Schenk A, Steindorf K, Bloch W, Hallek M, Joisten M, Zimmer P. Sleep problems and their interaction with physical activity and fatigue in hematological cancer patients during onset of high dose chemotherapy. Supportive Care in Cancer 2022. 30(1):167-176. DOI:10.1007/s00520-021-06377-5
• Proschinger S, Kuhwand P, Rademacher A, Walzik D, Warnke C, Zimmer P*, Joisten N*. Fitness, Physical activity, and Exercise in Multiple Sclerosis – A systematic review on current evidence for interactions with disease activity and progression. Journal of Neurology 2022. DOI:10.1007/s00415-021-10935-6.

2021

• Wolf F, Rademacher A, Joisten N, Proschinger S, Schlagheck M, Bloch W, Gonzenbach R, Kool J, Bansi J, Zimmer P. The aerobic capacity – fatigue relationship in persons with Multiple Sclerosis is not reproducible in a pooled analysis of two randomized controlled trials. Multiple Sclerosis and Related Disorders 2021. 58:103476. DOI: 10.1016/j.msard.2021.103476
• Isenmann E, Schumann M, Notbohm HL, Flenker U, Zimmer P. Hormonal response after masturbation in young helathy men – a randomized controlled cross-over trial. Basic and Clinical Andrology 2021. 31:32. DOI:10.1186/s12610-021-00148-2
• Winker M, Stössel S, Neu MA, Lehmann N, El Malki K, Paret C, Joisten N, Bloch W, Zimmer P*, Faber J*. Exercise reduces systemic immune inflammation index (SII) in childhood cancer patients. Supportive Care in Cancer 2021. doi: 10.1007/s00520-021-06719-3. DOI:10.1007/s00520-021-06719-3
• Herhaus B, Joisten N, Wessels I, Zimmer P*, Petrowski K*. How acute physical and psychological stress differentially influence the kynurenine pathway: a randomized cross-over trial.  Psychoneuroendocrinology 2021. 134:105433. DOI:10.1016/j.psyneuen.2021.105433
• Oberste M, de Waal P, Joisten N, Egbringhoff M, Javelle F, Bloch W, Zimmer P. Acute aerobic exercise to recover from mental exhaustion - a randomized controlled trial. Physiology & Behavior 2021. 241:113588., DOI: 10.1016/j.physbeh.2021.113588
• Pal A, Schneider J, Schlüter K, Steindorf K, Wiskemann J, Rosenberger F, Zimmer P. Different endurance exercises modulate NK cell cytotoxic and inhibiting receptors. European Journal of Applied Physiology 2021. 121(12):3379-3387. DOI:10.1007/s00421-021-04735-z
• Schlagheck M, Joisten N, Walzik D, Wolf F, Neil-Sztramko SE, Bansi J, Rademacher A, Zimmer P.  Systematic Review of Exercise Studies in Persons With Multiple Sclerosis: Exploring the Quality of Interventions According to the Principles of Exercise Training. Neurology and Therapy 2021. 10(2):585-607. DOI:10.1007/s40120-021-00274-z
• Joisten N, Gehlert S, Zimmer P. Is high-intensity interval training harmful to health? Trends in Endocrinology and Metabolism 2022. 33(2):85-86. DOI:10.1016/j.tem.2021.07.003
• Joisten N, Ruas LR, Braidy N, Guillemin GJ, Zimmer P. The kynurenine pathway in chronic diseases: Compensatory mechanism or driving force? Trends in Molecular Medicine 2021. 27(10):946-954. DOI: 10.1016/j.molmed.2021.07.006
• Javelle F, Bloch W, Knoop A, Guillemin GJ, Zimmer P. Toward a neuroprotective shift: Eight weeks of high intensity interval trainining reduces the neurotoxic kynurenine activity concurrently to impulsivity in emotionally impulsive humans – a randomized controlled trial. Brain Behaviour and Immunity 2021. 96:7-17.  DOI: 10.1016/j.bbi.2021.04.020
• Negaresh R, Gharakhanlou R, Sahraian MA, Abolhasani M, Motl RW, Zimmer P. Physical activity may contribute to brain health in multiple sclerosis: an MR volumetric and spectroscopy study. Journal of Neuroimaging 2021. 31(4):714-723. DOI:10.1111/jon.12869
• Schlagheck M, Wucherer A, Rademacher A, Joisten N, Proschinger S, Walzik D, Bloch W, Kool J, Gonzenbach R, Bansi J, Zimmer P. VO2peak response heterogeneity in persons with Multiple Sclerosis: To HIIT or not to HIIT? International Journal of Sports Medicine 2021. 42(14):1319-1328. DOI:10.1055/a-1481-8639
• Zimmer P, Hillebrand P. Wolf F, Joisten N, Walzik D, Hardt L, Großek A, Hartig P, Kierdorf F, Belz M, Tinschmann M, Kiesl D, Bloch W, Großophoff C, Hallek M, Böll B, Oberste M, elter T. Impact of induction chemotherapy on objective and self-perceived cognitive performance in patients suffering from hematological disorders. Leukemia & Lymphoma 2021. 21:1-5. DOI:10.1080/10428194.2021.1913151
• Stroehlein JK, Vieluf S, Zimmer P, Schenk A, Oberste M, Gölz C, van den Bongard F, Reinsberger C. Learning to Play Golf for Elderly People with Subjective Memory Complaints: Feasibility of a Single-Blinded Randomized Pilot Trial. BMC Neurology 2021. 21:200. DOI:10.1186/s12883-021-02186-9
• Rademacher A, Joisten N, Proschinger S, Bloch W, Gonzenbach R, Kool J, Langdon D, Bansi J, Zimmer P. Cognitive Impairment Impacts Exercise Effects on Cognition in Multiple Sclerosis. Frontier in Neurology 2021. 11:619500. DOI:10.3389/fneur.2020.619500
• Rademacher A, Joisten N, Proschinger S, Hebchen J, Schlagheck M, Bloch W, Kool J, Bansi J, Zimmer P. Do baseline cognitive status, participant specific characteristics and EDSS impact changes of cognitive performance following aerobic exercise intervention in multiple sclerosis? Multiple Sclerosis and Related Disorders 2021. 51:102905. DOI:10.1016/j.msard.2021.102905
• Walzik D, Joisten N, Zacher J, Zimmer P. Transferring clinically established immune inflammation markers into exercise physiology – focus on neutrophil-to-lymphocyte ratio, platelet-to-lymphocyte ratio and systemic immune-inflammation index. European Journal of Applied Physiology 2021.121(7):1803-1814. DOI:10.1007/s00421-021-04668-7
• Proschinger S, Winker M, Joisten N, Bloch W, Palmowski J, Zimmer P. The effect of exercise on regulatory T cells: A systematic review of human and animal studies with future perspectives and methodological recommendations. Exercise Immunology Review 2021. 27:142-166. http://www.eir-isei.de/2021/eir-2021-142-article.pdf
• Großek A, Elter T, Oberste M, Wolf F, Joisten N, Hartig P, Walzik D, Rosenberger F, Kiesl D, Wahl P, Bloch W, Zimmer P. Feasibility and Suitability of a Graded Exercise Test in Patients with Aggressive Hemato-Oncological Disease. Journal of Supportive Care in Cancer 2021. 29(8):4859-4866.  DOI:10.1007/s00520-021-06035-w
• Patt N, Kool J, Hersche N, Oberste M, Walzik D, Joisten N, Caminada D, Ferrara F, Gonzenbach R, Nigg C, Kamm CP, Zimmer P, Bansi J. High-intensity interval training and energy management education, compared with moderate continuous training and progressive muscle relaxation, for improving health-related quality of life in persons with multiple sclerosis: study protocol of a randomized controlled superiority trial with six months' follow-up. BMC Neurology 2021. 21:65. DOI:10.1186/s12883-021-02084-0
• Javelle F, Laborde S, Hosang T, Metcalfe A, Zimmer P. The importance of nature exposure and physical activity for psychological health and stress perception: evidence from the lockdown period during the COVID-19 pandemic 2021 (auf ResearchGate steht 2020) in France and Germany. Frontiers in Psychology 2021. 12:623946. DOI:10.3389/fpsyg.2021.623946
• Joisten N, Rademacher A, Warnke C, Proschinger S, Schenk A, Walik D, Knoop A, Thevis M, Steffen F, Bittner S, Gonzenbach R, Kool J, Bloch W, Bansi J, Zimmer P. Exercise diminishes plasma neurofilament light chain and reroutes the kynurenine pathway in MS. Neurology Neuroimmunology & Neuroinflammation 2021. 8:e982. DOI:10.1212/NXI.0000000000000982
• Oberste M, Sharma S, Bloch W, Zimmer P. Acute exercise-induced set shifting benefits in healthy adults and its moderators: a systematic review and meta-analysis. Frontiers in Psychology 2021. 12:528352. IF: 2,990. DOI:10.3389/fpsyg.2021.528352

2020

• Schenk A, Esser T, Knoop A, Thevis M, Heidenreich A, Herden J, Bloch W, Joisten N, Zimmer P. Effect of a single bout of aerobic exercise on kynurenine pathway metabolites and inflammatory markers in prostate cancer patients – a pilot randomized controlled trial. Metabolites 2020. 11:4. DOI: 10.3390/metabo11010004
• Umlauff L, Weil P, Zimmer P, Hackney AC, Bloch W, Schumann M. Oral Contraceptives Do Not Affect Physiological Responses to Strength Exercise. Journal of Strength and Conditioning 2020. 35(4):894-901. DOI:10.1519/JSC.0000000000003958
• Rumpf C, Proschinger S, Schenk A, Bloch W, Lampit A, Javelle F, Zimmer P. The effect of acute physical exercise on NK-cell cytolytic activity: A systematic review and meta-analysis. Sports Medicine 2020. 51(3):519-530. DOI: 10.1007/s40279-020-01402-9
• Joisten N, Schenk A, Zimmer P. Talking about physical »activity« or »inactivity«? The need of accurate activity controlling in exercise studies in rodents. Frontiers in Physiology 2020. 11:611193. DOI:10.3389/fphys.2020.611193
• Schenk A, Joisten N, Walzik D, Koliamitra C, Schoser D, Bloch W, Zimmer P. Acute exercise impacts AhR and PD-1 levels of CD8+ T-cells - Exploratory results from a randomized cross-over trial comparing endurance versus resistance exercise. European Journal of Applied Physiology 2020. 121(2):637-644. DOI: 10.1007/s00421-020-04552-w
• Javelle F, Wiegand M, Joormann J, Timpano KR, Zimmer P, Johnson SL. The German Three Factor Impulsivity Index: confirmatory factor analysis and ties to demographic and health-related variables. Personality and Individual Diffrences 2020. 171:110470. DOI:10.1016/j.paid.2020.110470
• Zimmer P, Javelle F, Lampit A. Comment on: “Effects of Exercise Training Interventions on Executive Function in Older Adults: A Systematic Review and Meta‑Analysis”. Sports Medicine 2020. 50(8):1451-1467. DOI: 10.1007/s40279-020-01369-7
• Joisten N, Proschinger S, Rademacher A, Schenk A, Bloch W, Warnke C, Gonzenbach R, Kool J, Bansi J, Zimmer P. High-intensity interval training reduces neutrophil-to-lymphocyte ratio in persons with multiple sclerosis during inpatient rehabilitation. Multiple Sclerosis Journal 2020. 27(7):1136-1139. DOI:10.1177/1352458520951382
• Proschinger S, Zimmer P. Multiple Sklerose: Immunbiologischer Einfluss von Sport. Deutsches Ärzteblatt 2020. 117 (27-28)., DOI:10.3238/PersNeuro.2020.07.08.05
• Joisten N, Walzik D, Metcalfe A, Bloch W, Zimmer P. Physical exercise as kynurenine pathway modulator in chronic diseases – Implications for immune- and energy homeostasis. International Journal of Tryptophan Research 2020. 13:1-9. DOI:10.1177/1178646920938688
• Pal A, Zimmer P, Wiskemann J, Steindorf K. Resistance exercise modulates Kynurenine pathway in pancreatic cancer patients. International Journal of Sports Medicine 2020. 42(1):33-40. DOI: 10.1055/a-1186-1009
• Banitalebi E, Mardaniyan Ghahfarrokhi M, Negaresh R, Kazemi A, Faramarzi M, Motl RW, Zimmer P. Exercise Improves Neurotrophins in Multiple Sclerosis Independent of Disability Status. Multiple Sclerosis and Related Disorders 2020. 43:102143. DOI:10.1016/j.msard.2020.102143
• Stössel S, Neu MA, Wingerter A, Bloch W, Zimmer P, Paret C, El Malki H, Baumann FT, Russo A, Henninger N, Lehmann, N, Otto H, Faber J. Benefits of exercise training for children and adolescents undergoing cancer treatment: Results from the randomized controlled MUCKI trial. Frontiers in Pediatrics 2020. 8:243. DOI:10.3389/fped.2020.00243
• Zimmer P. Mens sana in corporo sano (Editorial). Bewegungstherapie & Gesundheitswissenschaft 2020. 36 (2): 49. DOI:10.1055/a-1120-5929
• Oberste M, Zimmer P. Kognitionspsychologische Grundlagen und häufige methodische Fallstricke bei der Erforschung sport- und bewegungsinduzierter Effekte auf kognitive Leistungen. Bewegungstherapie & Gesundheitswissenschaft 2020. 36 (2): 52-57. DOI:10.1055/a-1120-5940
• Joisten N, Schumann M, Schenk A, Walzik D, Freitag N, Knoop A, Thevis M, Bloch W, Zimmer P. Acute hypertrophic but not maximal strenghth loading transiently enhancees the kynurenine pathway towards kynurenic acid. European Journal of Applied Physiology 2020. 120:1429–1436. DOI:10.1007/s00421-020-04375-9
• Schlagheck ML, Walzik D, Joisten N, Koliamitra C, Hardt L, Metcalfe AJ, Wahl P, Bloch W, Schenk A, Zimmer P. Cellular immune response to acute exercise: Comparison of endurance and resistance exercise. European Journal of Hematology 2020. 105(1):75-84., DOI:10.1111/ejh.13412
• Gharakhanlou R*, Wesselmann L*, Rademacher A, Lampitn A, Negaresh R, Kaviani M, Oberste M, Motl RW, Sandroff BM, Bansi J, Baker JS, Heesen C, Zimmer P*, Javelle F*. Exercise training and cognitive performance in persons with multiple sclerosis: a systematic review and multilevel meta-analysis of clinical trials. Multiple Sclerosis Journal 2020. 11:1352458520917935. DOI:10.1177/1352458520917935
• Oberste M, Medele M, Javelle F, Wunram LW, Walter D, Bloch W, Bender S, Fricke O, Joisten N, Walzik D, Großheinrich N, Zimmer P. Physical Activity for the Treatment of adolescent Depression: A systematic Review and Meta-analysis. Frontiers in Physiology 2020. 11:185. DOI:10.3389/fphys.2020.00185
• Joisten N, Kummerhoff F, Koliamitra C, Schenk A, Walzik D, Hardt L, Knoop A, Thevis M, Kiesl D, Metcalfe AJ, Bloch W, Zimmer P. Exercise and the Kynurenine pathway: Current state of knowledge and results from a randomized cross-over study comparing acute effects of endurance and resistance training. Exercise Immunology Review 2020. 26:24-42. PubMed
• Peukert X, Steindorf K, Schagen S, Runz A, Meyer P, Zimmer P. Hippocampus -related cognitive and affective impairments in patients with breast cancer -a systematic review. Frontiers in Oncology 2020. 10:147. DOI10.3389/fonc.2020.00147

2019

• Proschinger S, Joisten N, Rademacher A, Schlagheck M, Walzik D, Metcalfe A, Oberste M, Bloch W, Schenk A, Zimmer P. Influence of combined functional resistance and endurance exercise over 12 weeks on matrix metalloproteinase-2 serum concentration in persons with Relapsing-Remitting Multiple Sclerosis – A community-based randomized controlled trial. BMC Neurology 2019. 19(1):314. DOI:10.1186/s12883-019-1544-7
• Oberste M, Javelle F, Sharma S, Walzik D, Joisten N, Bloch W, Zimmer P. Effects and moderators of acute aerobic exercise on subsequent interference control: a systematic review and meta-analysis. Frontiers in Psychology 2019. 10:2616. DOI:10.3389/fpsyg.2019.02616
• Zimmer P, Schmidt ME, Berdel B, Wiskemann J, Kellner KH, Debus J, Ulrich CM, Opitz CA, Steindorf K. Resistance exercise reduces kynurenine levels in patients with breast cancer. Frontiers in Oncology 2019.  9:962. DOI:10.3389/fonc.2019.00962
• Wahl P, Zimmer P. Acute impact of recovery on the restoration of cellular immunological homeostasis. International Journal of Sports Medicine 2019. 41(1):12-20. DOI:10.1055/a-1015-0453
• Koliamitra C, Javelle F, Joisten N, Shimabukuro-Vornhagen A, Bloch W, Schenk A, Zimmer P. Do acute exercise-induced activations of the kynurenine pathway induce regulatory t-cells on the long-term? – a theoretical frame work supported by pilot data. Journal of Sports Science and Medicine 2019. 18(4):669-673. PMID: 31827351
• Oberste M, Sharma S, Zimmer P. Does a single bout of aerobic exercise improve set-shifting in healthy young adults? A systematic review and meta-analysis. Integrative and Complementary Medicine 2019. 4(3). IF: 1,21 DOI:10.21926/obm.icm.1903052
• Javelle F, Li D, Zimmer P, Johnson S. Dietary intake of tryptophan tied emotion-related impulsivity in humans. International Journal of Vitamins and Nutrition 2019. 91(1-2):69-76. DOI:10.1024/0300-9831/a000608
• Zimmer P, Bansi J, Rademacher A, Schlagheck ML, Walzik D, Proschinger S, Bloch w, Joisten N. Exercise-Neuro-Immunology – From Bench to Bedside. Deutsche Zeitschrift für Sportmedizin 2019. 70: 227-234. DOI:10.5960/dzsm.2019.392
• Zimmer P, Schenk A, Elter T. Molecular and biological mechanism of physical exercise on carcinogenesis. Der Gasteroenterologe 2019. 14:332–339. DOI:10.1007/s11377-019-0379-5
• Pal A, Zimmer P*, Schmidt M, Hummel M, Ulrich C, Wiskemann J, Steindorf K. No evidence for effect of Exercise on transcriptome of NK cells in breast cancer patients undergoing adjuvant therapy: Results from a pilot study. Frontiers in Physiology 2019. 10:959. DOI:10.3389/fphys.2019.00959
• Isenmann E, Ambrosio G, Joseph JF, Mazzarino M, de la Torre X, Zimmer P, Kazlauslas R, Goebel C, Botre FM, Diel P, Parr MK. Ecdysteroids as non-conventional anabolic agent: Performance Enhancement by Ecdysterone Supplementation in Humans. Archieves of Toxicology 2019. 93(7):1807-1816. DOI:10.1007/s00204-019-02490-x
• Schenk A, Koliamitra C, Bauer CJ, Schier R, Schweiger MR, Bloch W, Zimmer P. Impact of acute aerobic exercise on genome wide DNA Methylation in NK cells – a pilot study. Genes 2019. 10(5):380. DOI:10.3390/genes10050380
• Javelle F, Lampit A, Bloch W, Häussermann P, Johnson S, Zimmer P. A systematic review and meta-analysis of the effects of 5-hydroxytryptophan on distinct types of depression: Current evidence and future perspectives. Nutrition Reviews 2019. 78(1):77-88. DOI:10.1093/nutrit/nuz039
• Zimmer P, Joisten N, Schenk A, Bloch W. Impact of physical exercise on the kynurenine pathway in patients with cancer: Current limitations and future perspectives. Acta Oncologica 2019. 58(8):1116-1117. DOI:10.1080/0284186X.2019.1599139
• Joisten N, Walzik D, Schenk A, Bloch W, Zimmer P*, Wahl P. Aqua Cycling for Immunological Recovery after Intensive, Eccentric Exercise. European Journal of Applied Physiology 2019. 119(6):1369-1375. DOI:10.1007/s00421-019-04127-4
• Joisten N, Rademacher A, Bloch W, Schenk A, Oberste M, Dalgas U, Langdon D, Caminada D, Purdes MT, Gonzenbach R, Kool J, Zimmer P*, Bansi J. Influence of different rehabilitative aerobic exercise programs on (anti-) 1 inflammatory immune signaling, cognitive and functional capacity in persons with MS – Study protocol of a randomized controlled trial. BMC Neurology 2019. 19(1):37. DOI:10.1186/s12883-019-1267-9
• Mokhtarzade M, Agha-Alinejad H, Motl RW, Negaresh R, Zimmer P, Baker J. Weight control and physical exercise in persons with Multiple Sclerosis: Current knowledge and future perspectives. Complementary Therapies in Clinical Practice 2018. 43:240-246. DOI:10.1016/j.ctim.2019.02.006
• Bühl L, Abel T, Wolf F, Oberste M, Bloch W, Hallek M, Zimmer P. Feasibility and potential benefits of an exercise intervention in a male with Down syndrome undergoing high-dose chemotherapy for acute lymphoblastic leukemia – A case report. Integrative Cancer Therapies 2019. 18:1534735419832358. DOI:10.1177/1534735419832358
• Negaresh R, Motl RW, Zimmer P, Mokhtarzade M, Baker JS. Exercise Training Effects on Multiple Sclerosis Biomarkers of Central Nervous System and Disease Status: A Systematic Review of Intervention Studies. European Journal of Neurology 2019. 26(5):711-721. DOI:10.1111/ene.13929
• Eschke RC, Lampit A, Schenk A, Javelle F, Steindorf K, Diel P, Bloch W, Zimmer P. Impact of physical exercise on growth and progression of cancer in rodents – a systematic review and meta-analysis. Frontiers in Oncology 2019. 9:35. DOI:10.3389/fonc.2019.00035

2018

• Oberste M, Schaffrath N, Schmidt K, Bloch W, Jäger E, Steindorf K, Hartig P, Joisten N, Zimmer P. The impact of chemotherapy accompaigning high-intensity intervall training on cancer related cognitive impairments in breast cancer patients (the `Chemobrain in Motion`(CIM) study) – Study protocol of a randomized placebo-controlled trial. BMC Cancer 2018. 18(1):1071. DOI:10.1186/s12885-018-4992-3
• Schenk A, Pulverer W, Koliamitra C, Bauer C, Schier, Böttiger B, Bloch W, Zimmer P. Acute exercise increases the expression of the activating natural killer cell receptor KIR2DS4 by promoter demethylation. International Journal of Sports Medicine 2018. 40(1):62-70. DOI:10.1055/a-0741-7001
• Metcafle A, Koliamitra C, Javelle F, Bloch W, Zimmer P. Acute and chronic effects of exercise on the kynurenine pathway in humans – A brief review and future perspectives. Behavior & Physiology 2018. 194:583-587. DOI:10.1016/j.physbeh.2018.07.015
• Negaresh R, Mokhtarzade M, Motl R, Majdinasab N, Ranjnbar R, Khodadoost M, Zimmer P, Baker J, Patel D. Effect of Short-Term Interval Exercise Training on Fatigue, Depression and Fitness in Normal Weight vs. Overweight person with Multiple Sclerosis Explore: The Journal of Science and Healing 2018. 15(2):134-141. DOI:10.1016/j.explore.2018.07.007
• Negaresh R, Motl R, Mohhtarzade M, Dalgas U, Patel D, Shamsi M, Majdinasab N, Ranjnbar R, Zimmer P, Baker J. Effects of exercise training on cytokines and adipokines in multiple Sclerosis: A systematic review. Multiple Sclerosis and Related Disorders 2018. 24:91-100. DOI:10.1016/j.msard.2018.06.008
• Mohtarzade M, Motl R, Negaresh R, Zimmer P, Khodadoost M, Baker J, Patel D, Majdinasab N, Ranjnbar R. Exercise-induced changes in neurotrophic factors and markers of blood-brain barrier permeability are moderated by weight status in multiple sclerosis. Neuropeptides 2018. 70:93-100. DOI:10.1016/j.npep.2018.05.010
• Bizjak D, Jacko D, Zimmer P, Gehlert S, Bloch W, Grau M. Acute alterations in the hematological and hemorheological profile induced by resistance training and possible implication for microvascular functionality. Microvascular Research 2018. 118:137-143. DOI:10.1016/j.mvr.2018.03.007
• Majdinasab N, Motl R, Mokhtarzade M, Zimmer P, Ranjbar R, Keytsman C, Cullen T, Negaresh R, Baker J. Acute Responses of Cytokines and Adipokines to Aerobic Exercise in Women with Relapsing vs. Remitting Multiple Sclerosis. Complementary Therapies in Clinical Practice 2018. 31:295-301. IF: 1,701 DOI:10.1016/j.ctcp.2018.03.004
• Steindorf K, Schmidt ME, Zimmer P. Sport und Bewegung mit und nach Krebs – wer profitiert, was ist gesichert? Deutsche Medizinische Wochenschrift 2018. 145(5):309-315. DOI:10.1055/a-0842-4464
• Gutmann B*, P. Zimmer P*, Hülsdünker T, Lefebvre J, Binnebößel S, Oberste M, Bloch W, Strüder HK, Mierau A. The effects of exercise intensity and post-exercise recovery time on cortical activation as revealed by EEG alpha peak frequency. Neuroscience letters 2018. 668:159-163. DOI:10.1016/j.neulet.2018.01.007
• Bansi J, Koliamitra C, Bloch W, Joisten N, Schenk A, Watson M, Kool J, Langdon D, Dalgas U, Kesselring J, Zimmer P. Persons with secondary progressive and relapsing remitting multiple sclerosis reveal different responses of Tryptophan metabolism to acute endurance exercise and training. Journal of Neuroimmunology 2018. 314:101-105. DOI:10.1016/j.jneuroim.2017.12.001
• Zimmer P, Trebing S, Streckmann F, Timmers-Trebing U, Schenk A, Paust R, Bloch W, Rudolph R, Baumann FT. Eight-week, multimodal exercise counteracts a progress of chemotherapy-induced peripheral neuropathy and improves balance and strength in metastasized colorectal cancer patients: a randomized controlled trial. Journal of Supportive Care in Cancer 2018. 26(2):615-624. DOI:10.1007/s00520-017-3875-5
• Wunram H, Hamacher S, Hellmich M, Volk M, Jänicke F, Reinhard F, Bloch W, Zimmer P, Graf C, Schönau E, Lehmkuhl G, Bender S, Fricke O. Whole body vibration added to treatment as usual is effective in adolescents with depression: a partly randomized, three-armed clinical trial in inpatients. European Child & Adolescent Psychiatry 2018. 27(5):645-662. DOI:10.1007/s00787-017-1071-2
• Zimmer P, Baumann FT, Oberste M, Schmitt J, Joisten N, Hartig P, Schenk A, Kuhn R, Bloch W, Reuss-Borst M. Influence of personalized exercise recommendations during rehabilitation on the sustainability of objectively measured physical activity levels, fatigue and fatigue-related biomarkers in patients with breast cancer. Integrative Cancer Therapies 2018. 17(2):306-311. DOI:10.1177/1534735417713301

2017

• Oberste M, Hartig P, Bloch W, Elsner B, Predel HG, Ernst B, Zimmer P. Control group paradigms in studies investigating acute effects of exercise on cognitive performance – An experiment on expectation-driven placebo effects. Frontiers of Human Neuroscience 2017. 11:600. DOI:10.3389/fnhum.2017.00600
• Zimmer P, Bloch W, Schenk A, Oberste M, Riedel S, Kool J, Langdon D, Dalgas U, Kesselring J, Bansi J. High-intensity interval exercise improves cognitive performance and reduces matrix metalloproteinases-2 serum levels in persons with multiple sclerosis - A randomized controlled trial. Multiple Sclerosis Journal 2017. 1:1352458517728342. DOI:10.1177/1352458517728342
• Koliamitra C, Holtkamp B, Zimmer P, Bloch W, Grau M. Impact of training volume and intensity on RBC-NOS/NO pathway and endurance capacity. Biorheology 2017. 54(1):37-50. DOI:10.3233/BIR-16121
• Zimmer P, Bloch W, Kieven M, Lövenich L, Lehmann J, Holthaus M, Theurich S, Schenk A. Serotonin shapes the migratory potential of NK-cells – An in vitro approach. International Journal of Sports Medicine 2017. 38(11):857-863. DOI:10.1055/s-0043-113042
• Zimmer P, Schenk A, Kieven M, Holthaus M, Lehmann J, Lövenich L, Bloch W. Exercise induced alterations in NK-cell cytotoxicity – methodological issues and future perspectives. Exercise Immunology Review 2017. 23:66-81. PubMed
• Zimmer P, Binnebößel S, Bloch W, Hübner ST, Predel HG, Wright P, Stritt C, Oberste M Exhaustive exercise alters thinking times in a Tower of London task in a time-dependent manner. Frontiers in Physiology 2017. 7:694. DOI:10.3389/fphys.2016.00694
• Schaffrath N, Oberste M, Zimmer P. Effects of Exercise Interventions and Physical Activity Behavior on Cancer Related Cognitive Impairments: An update. Current Opinion in Supportive and Palliative Care 2017. 11(1):52-59. DOI:10.1097/SPC.0000000000000249

2016

• Oberste M, Bloch W, Hübner ST, Zimmer P. Do reported effects of acute aerobic exercise on subsequent higher cognitive performances remain if tested against an instructed self-myofascial release training control group? A randomized controlled trial. PLoS One 2016. 11(12):e0167818. DOI:10.1371/journal.pone.0167818
• Freese J, Pardi D, Ruiz-Nunez B, Schwarz S, Heynck R, Renner R, Zimmer P, Lötzerich H. Back to the Future. Metabolic Effects of a 4-Day Outdoor Trip Under Stimulated Paleolithic Conditions – New Insights from The Eifel Study. Journal of Evolution and Health 2016. DOI:10.15310/2334-3591.1035
• Pesendorfer LM, Zimmer P, Galvao DA, Zopf EM, Bloch W, Baumann FT. Impact of Physical Inactivity on the Multifactorial Process of Developing Cancer-Related Cognitive Impairments. Journal of Cancer Science & Therapy 2016. 8:222-227. DOI:10.4172/1948-5956.1000417
• Filipovic A, Grau M, Kleinöder H, Zimmer P, Hollmann W, Bloch W. Effects of a whole-body electrostimulation program on strength, sprinting, jumping, and kicking capacity in elite soccer players. Journal of Sports Science & Medicine 2016. 15(4):639-648. PubMed
• Zimmer P, Stritt C, Bloch W, Schmidt FP, Hübner ST, Binnebößel S, Schenk A, Oberste M. The effects of different aerobic exercise intensities on serum serotonin concentrations and their association with Stroop-task performance – A randomized controlled trial. European Journal of applied Physiology 2016. 116(10):2025-2034. DOI:10.1007/s00421-016-3456-1
• Zimmer P, Oberste M, Bloch W, Schenk A, Joisten N, Hartig P, Wolf F, Baumann FT, Garthe A, Hallek M, Elter T. Impact of aerobic exercise training during chemotherapy on cancer related cognitive impairments in patients suffering from acute myeloid leukemia or myelodysplastic syndrome – Study protocol of a randomized placebo-controlled trial. Contemporary Clinical Trials 2016. 49:1-5. DOI:10.1016/j.cct.2016.05.007
• Zimmer P, Baumann FT, Oberste M, Wright P, Garthe A, Schenk A, Elter T, Galvao DA, Bloch W, Hübner ST, Wolf F. Effects of exercise interventions and physical activity behavior on cancer related cognitive impairments – a systematic review. Biomed Research International 2016. 1820954. DOI:10.1155/2016/1820954
• Schenk A, Bloch W, Zimmer P. Natural killer cells – An epigenetic perspective of development and regulation. International Journal of Molecular Science 2016. 17(3):326. DOI:10.3390/ijms17030326
• Zimmer P, Baumann FT, Bloch W, Zopf EM, Schulz S, Latch J, Schollmayer F, Shimabukuro-Vornhagen A, von Bergwelt-Baildon M, Schenk A. Impact of a half marathon on cellular immune system, pro-inflammatory cytokine levels and recovery behavior of breast cancer patients in the aftercare compared to healthy controls. European journal of haematology 2016. 96(2):152-159. DOI:10.1111/ejh.12561
• Giesen E, Zimmer P, Bloch W. Effects of an exercise program on physical activity level and quality of life in patients with severe alcohol dependence. Alcoholism Treatment Quarterly 2016. 34:63-78. DOI:10.1080/07347324.2016.1113109

2015

• Zimmer P, Bloch W, Schenk A, Zopf EM, Hildebrandt U, Streckmann F, Beulertz J, Koliamitra C, Schollmayer F, Baumann F. Exercise induced natural killer cell activation is driven by epigenetic modifications. International Journal of Sports Medicine 2015. 36(6):510-515. DOI:10.1055/s-0034-1398531
• Zimmer P, Oberste M, Bloch W. Einfluss von Sport auf das zentrale Nervensystem-Molekulare und zelluläre Wirkmechanismen. Deutsche Zeitschrift für Sportmedizin 2015. 66:42-49. DOI:10.5960/dzsm.2015.164
• Zimmer P, Bloch W. Physical exercise and epigenetic adaptations of the cardiovascular system. Herz 2015. 40(3):353-360. DOI:10.1007/s00059-015-4213-7
• Zimmer P, Borowik S, Bloch W, Giesen A, Gerland L, Schenk A, Elter T, Baumann FT. Krafttraining gleich Krafttraining? Neue Erkenntnisse für die onkologische Trainingstherapie. Deutsche Zeitschrift für Onkologie 2015. 47(2):70-74. DOI:10.1055/s-0035-1547546
• Bobylev I, Elter T, Schneider C, Wunderlich G, Zimmer P, Streckmann F, Fink GR, Lehmann HC. Chemotherapy-induced peripheral neuropathy. Fortschritte der Neurologie-Psychiatrie 2015. 83(8):427-436. DOI:10.1055/s-0035-1553475

2014

• Zimmer P, Mierau A, Bloch W, Strüder HK, Hülsdünker T, Schenk A, Fiebig L, Baumann FT, Hahn M, Reinart N, Hallek M, Elter T. Post-chemotherapy cognitive impairment in patients with B-cell Non-Hodgkin-Lymphoma: a first comprehensive approach to determine cognitive impairments after treatment with rituximab, cyclophosphamide, doxorubicin, vincristine and prednisone or rituximab and bendamustine. Leukemia and Lymphoma 2014. 56(2):347-352. DOI:10.3109/10428194.2014.915546
• Streckmann F, Zopf EM, Lehmann HC, May K, Rizza J, Zimmer P, Gollhofer A, Bloch W, Baumann FT. Exercise intervention studies in patients with peripheral neuropathy- a systematic review. Sports Medicine 2014. 44(9):1289-1304. DOI:10.1007/s40279-014-0207-5
• Zimmer P, Baumann FT, Bloch W, Schenk A, Koliamitra C, Jensen P, Mierau A, Hülsdünker T, Reinart N, Hallek M, Elter T. Impact of exercise on pro inflammatory cytokine levels and epigenetic modulations of tumor-competitive lymphocytes in Non-Hodgkin-Lymphoma patients-randomized controlled trial. European journal of haematology 2014. 93(6):527-532. DOI:10.1111/ejh.12395
• Scharhag-Rosenberger F, Becker T, Streckmann F, Schmidt K, Berling A, Bernardi A, Engeroff T, Exner A, Gutekunst K, Hofmeister D, Jensen W, Kähnert H, Kneis S, Limbach M, Mau-Möller A, Röcker K, Schmidt ME, Schmidt T, Stöckel T, Wehrle A, Wiskemann J, Zimmer P, Zopf E, Steindorf K. Wissenschaftliche Studien zu körperlichem Training bei onkologischen Patienten: Empfehlungen zu den Erhebungsmethoden. Deutsche Zeitschrift für Sportmedizin 2014. 65(11):304-313. DOI:10.5960/dzsm.2014.148

2013

• Zimmer P, Jäger E, Bloch W, Zopf EM, Baumann FT. Influence of a six month endurance exercise program on the immune function of prostate cancer patients undergoing Antiandrogen- or Chemotherapy: Design and rationale of the ProImmun study. BMC Cancer 2013. 13(1):272. DOI:10.1186/1471-2407-13-272
• Zimmer P, Baumann F T, Ebel J, Zopf EM, Bloch W, Elter T. Feasibility of an isometric maximal voluntary contraction (MVC) test in hematological cancer patients during thrombocytopenia. Journal of Sports Medicine 2013. 470489. DOI:10.1155/2013/470489
• Baumann FT, Bloch W, Weissen A, Brockhaus M, Beulertz J, Zimmer P, Streckmann F, Zopf EM. Physical Activity in Breast Cancer Patients during Medical Treatment and in the Aftercare- a Review. Breast Care 2013. 8:330-334. DOI:10.1159/000356172
• Baumann FT, Zimmer P, Westhof T, Krohe S, Stempin A, Müsgens M, Krause A, Beulertz J, Zopf E, Bloch W, Jäger E. A bicycle tour over 1408 km with prostate cancer patients – results of a pilot study. European Review of Aging and Physical Activity 2013. 10(1):19-24. DOI:10.1007/s11556-012-0119-z
• Bloch W, Zopf E, Zimmer P, Baumann FT. Role of physical activity in tumor patients and possible underlying mechanisms. European Review of Aging and Physical Activity 2013. 10(1):25-33. DOI:10.1007/s11556-012-0106-4

2012

• Zimmer P. Körperliche Aktivität und das Immunsystem onkologischer Patienten. Forum Onkologische Pflege 2012. 1:18-20. DOI:10.1055/s-0032-1327054
• Zimmer P, Baumann FT. Cancer related fatigue- Wirkungsweisen körperlicher Aktivität auf molekularer Ebene. Onkologische Pharmazie 2012. 14(2):12-15. http://www.dgop.org/download/op_0212.pdf#page=2
• Bloch W, Zimmer P. Epigenetik und Sport. Deutsche Zeitschrift für Sportmedizin 2012. 63(6):163-167. DOI:10.5960/dzsm.2012.024
• Bloch W, Suhr F, Zimmer P. Molecular mechanisms of exercise-induced cardiovascular adaptations: Influence of epigenetics, mechanotransduction and free radicals. Herz 2012. 37(5):508-515. DOI: 10.1007/s00059-012-3637-6
• Baumann FT, Zimmer P*, Finkenberg K, Hallek M, Bloch W, Elter T. Influence of endurance exercise on the risk of pneumonia and fever in leukemia and lymphoma patients undergoing high dose chemotherapy. A pilot study. Journal of Sports Science and Medicine 2012. 11(4):638-642. PubMed

*shared first/last authorship

2021

• Zimmer P, Schenk A, Proschinger S. Epigenetics in Exercise Science and Sports Medicine 2^nd Edition. Medical Epigenetics (Ed:  Tollefsbol). Elsevier: Amsterdam 2021; 491-509. DOI:10.1016/B978-0-12-823928-5.00005-0

2020

• Zimmer P, Appell HJ (Ed.). Funktionelle Anatomie. Springer Medizin Verlag: Heidelberg 2020. DOI:10.1007/978-3-662-61482-2

2018

• Baumann FT, Däggelmann J, Streckmann F, Zimmer P, Zopf EM. Tumorerkrankungen. Praxisbuch Sport in Prävention und Therapie (Ed. Mooren, Reimers). Elsevier: München 2018; 197. DOI:10.1016/B978-3-437-24275-5.00011-7
• Baumann FT, Zimmer P. Mammakarzinom. Praxisbuch Sport in Prävention und Therapie (Ed. Mooren, Reimers). Elsevier: München 2018; 197-199. ISBN: 9783437453519

2017

• Zimmer P, Schenk A, Bloch W. Genetische und epigenetische Aspekte in Bezug auf körperliche Aktivität und Gesundheit. Körperliche Aktivität und Gesundheit- Präventive und therapeutische Ansätze der Sportmedizin (Ed. Banzer). Springer: Berlin 2017, Heidelberg. 93(6): 527-532. DOI:10.1007/978-3-662-50335-5_25

2016

• Schier R, Zimmer P, Riedel B. Perioperative Inflammation and Microcirculation in Surgery: Clinical Strategies for Improved Surgical Outcomes. Microcirculation in health and disease (Ed. Lenasi). InTech open access publisher: 2016 Apr 20;20(Suppl 2):94. DOI:10.5772/64435
• Zimmer P, Schenk A, Bloch W. Epigenetics in Exercise Science and Sports Medicine. Medical Epigenetics (Ed:  Tollefsbol). Elsevier: Amsterdam 2016; 515-530. DOI:10.1016/B978-0-12-803239-8.00029-6

2015

• Baumann F, Beulertz J, Streckmann F, Zimmer P, Zopf E. Tumorerkrankungen. Prävention und Therapie durch Sport. 2. Auflage (Ed. Reimers, Broocks, Knapp, Mewes, Mooren, Reuter, Tettenborn, Thürauf). Urban & Fischer Verlag: München 2015; 263-268. DOI:10.1016/B978-3-437-24275-5.00011-7
• Zimmer P, Giesen E, Bloch W. Bedeutung bewegungsgestützter Therapieverfahren zur Behandlung von komorbid erkrankten Suchtpatienten in der Forensik - Teil 1. neurowissenschaftliche Aspekte. Straftäter behandeln (Ed. Saimeh). MWV Medizinisch Wissenschaftliche Verlagsgesellschaft mbH & Co. KG: Berlin 2015. ISBN: 978-3-95466-228-9
• Kunert HJ, Bloch W, Zimmer P, Norra C. Bedeutung bewegungsgestützter Therapieverfahren zur Behandlung von komorbid erkrankten Suchtpatienten in der Forensik - Teil 2 klinische Aspekte. Straftäter behandeln (Ed. Saimeh). MWV Medizinisch Wissenschaftliche Verlagsgesellschaft mbH & Co. KG: Berlin 2015. ISBN: 978-3-95466-228-9

2012

• Zimmer P, Rüffer J U. Fatigue-Syndrom. Sport und körperliche Aktivität in der Onkologie (Ed: Baumann, Jäger Bloch). Springer: Berlin, Heidelberg 2012; 69-78. ISBN: 978-3-642-25066-8
• Zimmer P, Zopf E, Baumann F T. Tumorkachexie. Sport und körperliche Aktivität in der Onkologie (Ed: Baumann, Jäger, Bloch). Springer: Berlin, Heidelberg 2012; 89-97. DOI:10.1007/978-3-642-25066-8_9
• Baumann FT, Zopf E, Elter T, Zimmer P, Beulertz J, Bloch W. Sport und körperliche Aktivität in der Onkologie (Ed: Baumann, Jäger, Bloch). Springer: Berlin, Heidelberg 2012; 31-40. DOI:10.1007/978-3-642-25066-8